Biomarker Solutions




Among functional biomarkers, electrophysiology (EEG) is the work horse in CNS drug research. EEG is highly sensitive to drug effects and it is a classic "translational" biomarker because it allows a direct comparison between (small) animals and humans. An additional advantage is that test-retest reliability is high and that center measurement effects are negligible in multicenter settings. Most importantly, EEG is highly sensitive to detect drug effects.

  • We offer:
  • Standard EEG with 32-channel EEG systems from Brain Products (BrainAmp DC®). Upon request, amplifiers with up to 64 channel recordings can be provided as well.
  • Study set-up and EEG-data acquisition incl. QC/monitoring (in established multicenter settings)
  • Data analysis: clinical EEG evaluation, power spectra, vigilance staging, spectral coherence, source localization (LORETA), event-related potentials (ERPs): P50, N100, MMN, P300 incl. time-frequency analyses
  • Pharmaco-EEG: established subanesthetic ketamine challenge, nicotine challenge
  • Normal reference database: N > 3000. Patient reference database (Schizophrenia, MCI, ADHD): > 800
  • Special offer: Simultaneous EEG with functional magnetic resonance imaging (fMRI) (see Functional Magnetic Resonance Imaging)

© PI-PharmaImage Germany GmbH 2017 | Webdesign: blickpunkt x, Köln

Cookies make it easier for us to provide you with our services. With the usage of our services you permit us to use cookies.
More information Ok Decline