Biomarker Solutions

Biomarkers

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Biomarkers are the bridge between basic and clinical research. It enables us to speed up the process of drug development (Winterer, G. The Handbook of Neuropsychiatric Biomarkers. Springer 2009). An NIH (National Institute of Health) study group committed to the following definition of biomarkers: A characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention (Biomarkers Definitions Working Group. Clin Pharmacol Ther 2001). This biomarker definition is relatively broad encompassing both physiological indicators (functional biomarkers) such as blood pressure, heart rate and brain function measures as well as molecular measures (molecular biomarkers) like gene expression, proteins, immunological markers etc.

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